Pantethine (Pantesin®)

This supplement helps supplement cognition and helps you achieve your ideal body composition.

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As its name implies, pantethine is similar in structure to the essential vitamin pantothenic acid which is known as vitamin B-5. Pantethine metabolizes to pantothenic acid and cysteamine, both of which have powerful benefits. [1]

Dietary sources of this vitamin are plentiful, with avocados, meats, whole grains, eggs, and legumes being the most B-5 rich foods. [2]

Because pantethine metabolizes to pantothenic acid and cysteamine while boasting high bioavailability, supplemental pantethine can fulfill daily vitamin B-5 needs while bringing additional benefits.

Body Composition

Vitamin B-5 is vital for cellular functions of all mammals. [2] Metabolic functions utilize vitamin B-5 to break down proteins, carbohydrates, and fats for energy. [2] Pantethine supplementation can leverage metabolic processes to benefit metabolism.

Pantethine can promote muscle retention and lean mass as well. [3]


By supplementing plasma vitamin B-5 levels, and subsequently CoA, pantethine helps provide key neurotransmitter intermediates. [3] CoA helps carry acyl groups to provide the acetyl- portion of vital neurotransmitters such as acetylcholine and N-Acetylserotonin. [3]

Pantethine vs Pantothenic Acid

Since pantethine is similar to vitamin B-5, you may be wondering why you can’t take vitamin B-5 instead. While vitamin B-5 and pantethine share some benefits, vitamin B-5 cannot exert the same effects on lipids that pantethine can.

Suggested Dosage

The recommended dosage for our pantethine formulation is 545mg per day. This will yield 300mg of pantethine.


What are some products that go well with pantethine?

  • Berberine
  • CoQ10
  • Fish oil

Do I need to refrigerate pantethine?

No, you do not need to refrigerate pantethine.

Pantesin® is a registered trademark of Kyowa Pharma Chemical Co., Ltd.


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